Monoclonal antibodies that bind OCIF
US6919434B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 23, 1999 |
| Grant date | Jul 19, 2005 |
| Priority date | — |
| Expiry date | Jun 23, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/81
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A protein which inhibits osteoclast diffraction and/or maturation and a method for producing the protein. The protein is produced by human embryonic lung fibroblasts and has a molecular weight of about 60 kD and about 120 kD under non-reducing conditions and about 60 kD under reducing conditions an SDS-polyacrylamide gel electrophoresis. The protein can be isolated and purified from the culture medium of fibroblasts. Furthermore, the protein can be produced by gene engineering. The present invention includes cDNA for producing the protein by gene engineering, antibodies having specific affinity for the protein or a method for determining protein concentration using these antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.