Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives

US6921822B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Hans-Christian Militzer · Odenthal, DE
• Boris Bosch
• Markus Eckert · Bad Mergentheim, DE
• Benjamin Meseguer · Tarragona, ES

Key dates

• Filing date: Jun 9, 2003
• Grant date: Jul 26, 2005
• Expiry date: Oct 17, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/07
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for preparing stereoisomerically enriched 4-aryl-4-hydroxybutanoic acid derivatives by reducing 4-aryl-4-ketobutanoic acid derivatives in the presence of ruthenium-containing catalysts.