Patent · US Expired

Separation column devices and fabrication methods

US6923907B2 · kind B2 · utility

75Cited by
57References
57Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 13, 2003
Grant dateAug 2, 2005
Priority date
Expiry dateOct 15, 2023

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2030/565
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Pressure-driven microfluidic separation devices, such as may be used for performing high performance liquid chromatography, are provided. Multiple separation columns may be defined in a single device and packed with stationary phase material retained by porous frits. One or more splitters may be provided to distribute slurry and/or mobile phase among multiple separation columns. In one embodiment, separation devices are substantially planar and fabricated with multiple device layers. Systems and methods employing slurry for packing separation devices are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.