Method and means for producing high titer, safe, recombinant lentivirus vectors
US6924144B2 · kind B2 · utility
4Cited by
18References
17Claims
0Family size
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Key dates
| Filing date | Jul 10, 2002 |
| Grant date | Aug 2, 2005 |
| Priority date | — |
| Expiry date | Sep 24, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Lentiviral vectors modified at the 5′ LTR or both the 5′ and 3′ LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.