Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
US6924265B2 · kind B2 · utility
1Cited by
1References
4Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 9, 2001 |
| Grant date | Aug 2, 2005 |
| Priority date | — |
| Expiry date | Mar 17, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to peptides and peptide analogues designed from HFE protein. In particular, it relates to peptides and peptide analogues designed from an alpha-1 region of HFE protein which lowers the binding affinity of transferrin receptor for transferrin. Such compounds mimic HFE protein function, and reduce iron uptake and/or accumulation by a cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.