Method for producing diphosphines and the use thereof

US6924389B2 · kind B2 · utility

Assignee

• OXENO OLEFINCHEMIE GMBH · DE

Inventors

• Ralf Jackstell · Rostock, DE
• Holger Klein · Rostock, DE
• Matthias Beller · Ostseebad Nienhagen, DE
• Klaus-Diether Wiese · Haltern am See, DE
• Cornelia Borgmann · Frankfurt, DE

Key dates

• Filing date: Mar 19, 2002
• Grant date: Aug 2, 2005
• Expiry date: Mar 19, 2022

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01J2540/225
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Diphosphine of formula IR1R2P—H2C—Ar—CH2PR1R2  (I)are prepared by a process that comprises a) reacting a dimethyl compound of formula IIH3C—Ar—CH3  (II)with a base and an N-substituted aminophosphorous halide to form bis(aminophosphinomethyl) compound of the formula IIIR3R4P—H2C—Ar—CH2—PR3R4  (III)b) reacting the compound of formula III with HCl to form bis(dichlorophosphinomethyl) compound of formula IVCl2P—H2C—Ar—CH2—PCl2  (IV)and c) reacting the compound of formula IV with an organometallic reagent to give the product compound of formula I, wherein groups R1 and R2 are each, independently of one another, a substituted or unsubstituted aromatic, heteroaromatic or aliphatic hydrocarbon group and may have a covalent bond connecting them and Ar is a substituted or unsubstituted aromatic or heteroaromatic hydrocarbon group an R3 and R4 are each, independently of one another, an N-substituted alkylamino or arylamino group.