Metal compounds, mixed or sulphated, as phosphate binders
US6926912B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 18, 1998 |
| Grant date | Aug 9, 2005 |
| Priority date | — |
| Expiry date | Sep 18, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC01G49/009
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-aluminum containing mixed metal compound for pharmaceutical use, which may, for example, be a mixed metal hydroxy carbonate containing magnesium and iron, and may have a hydrotalcite structure, preferably a non-aged hydrotalcite structure. Other metals, including, for example, calcium, lanthanum and cerium, may also be used. Metal sulphate compounds, especially calcium sulphate, lanthanum sulphate and/or cerium sulphate, compounds are also useful. The mixed metal compounds have a phosphate binding capacity of at least 30%, by weight, based on the test methods 1, 2 or 3, described in the specification, over a pH range from 3 to 7, such as from 2 to 8. The compound is especially useful in the treatment of hyperphosphataemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.