Modified dendritic cells and use therefor
US6929792B1 · kind B1 · utility
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16Claims
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Key dates
| Filing date | Mar 31, 2000 |
| Grant date | Aug 16, 2005 |
| Priority date | — |
| Expiry date | Mar 31, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N5/0639
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides isolated dendritic cells genetically modified to express a selectin polypeptide, optionally treated with activated platelets or membrane microparticles thereof. The invention also provides isolated platelet modified dendritic cells. Methods for delivering the modified dendritic cells to peripheral lymph nodes and methods for using the modified dendritic cells to stimulate immune responses also are provided. Vaccine compositions containing the modified dendritic cells also are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.