Gluconobacter oxydans 2-ketoreductase enzyme and applications thereof
US6929935B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 16, 2002 |
| Grant date | Aug 16, 2005 |
| Priority date | — |
| Expiry date | Feb 15, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to an novel Gluconobacter oxydans 2-ketoreductase useful for the synthesis of chiral alcohols. Also related are isolated nucleic acids encoding G. oxydans 2-ketoreductase enzymes, and enzyme fragments and variants thereof, as well as vectors and host cells comprising these nucleic acids. Further related are isolated G. oxydans 2-ketoreductase polypeptides, and fragments and variants thereof, and antibodies that specifically bind to G. oxydans 2-ketoreductase polypeptides, fragments, or variants. The invention also relates to methods of obtaining isolated G. oxydans 2-ketoreductase nucleic acids, polypeptides, and antibodies, and methods of using G. oxydans 2-ketoreductase in various reactions for industrial or pharmaceutical applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.