Patent · US Expired

Conformationally constrained backbone cyclized somatostatin analogs

US6930088B2 · kind B2 · utility

7Cited by

15References

18Claims

0Family size

Assignee

Peptor Ltd. · IL

Inventors

Vered Hornik · Rehovot, IL
Michel Afargan · Raanana, IL
Gary Gellerman · Rishon LeZion, IL

Key dates

Filing date	Dec 13, 2000
Grant date	Aug 16, 2005
Priority date	—
Expiry date	Jan 24, 2023

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Novel peptides which are conformationally constrained backbone cyclized somatostatin analogs, having somatostatin receptor subtype selectivity are disclosed. These patterns or receptor subtype selectivity provide compounds having improved therapeutic utility. Methods for synthesizing the somatostatin analogs and for screening of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comprising somatostatin analogs, and methods of using such compositions are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.