Method of inducing or enhancing chondrogenesis with extracellular matrix containing BMP-4
US6932977B2 · kind B2 · utility
13Cited by
6References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 13, 2001 |
| Grant date | Aug 23, 2005 |
| Priority date | — |
| Expiry date | Mar 13, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and composition are provided for inducing or enhancing chondrogenesis in vivo or in vitro. The method is performed by exposing the cells in vitro or in vivo to an extracellular matrix comprising of type I collagen, type II collagen or a mixture of type I collagen or type II collagen and hyaluronate and further containing BMP-4 or a combination of BMP-4 and GDF-5.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.