Use of azetidinone compounds
US6933107B2 · kind B2 · utility
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38References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 15, 2003 |
| Grant date | Aug 23, 2005 |
| Priority date | — |
| Expiry date | May 15, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4704
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.