Reagents and methods for automated hybridization

US6933117B2 · kind B2 · utility

Assignee

• Ventana Medical Systems, Inc. · US

Inventors

• Catherine Wolf · Mulhouse, FR
• Hiroaki Nitta · Sakata, JP
• Thomas Grogan · Tucson, US
• Jacques Cavadenti · Strasbourg, FR
• Lidija Pestic-Dragovich · Tucson, US
• Anthony L. Hartman · Tucson, US
• Angela Sattler · Tucson, US
• Jennifer Wong · Tucson, US

Key dates

• Filing date: Apr 30, 2002
• Grant date: Aug 23, 2005
• Expiry date: Apr 30, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6841
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention provides novel reagents, reagent kits, and methods for automated hybridization. More particularly, the invention provides reagents, reagent kits, and methods for automated in situ hybridization and automated hybridization on a microarray. The use of automated instruments for in situ hybridization and microarray hybridization dramatically reduces the amount of labor and time involved and also facilitates standardization of protocols and consistency between results.