Derivatives of isoindigo, indigo and indirubin and methods of treating cancer
US6933315B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Jun 10, 2004 |
| Grant date | Aug 23, 2005 |
| Priority date | — |
| Expiry date | Jun 10, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound called NATURA, which is a derivative of Isoindigo is useful in aiding the general health of a patient and specifically is beneficial in preventing or treating cancer. This compound and other related Isoindigo, Indigo and Indirubin derivatives are designed such that the bioactivity or bioavailability of the compound is increased. Methods of synthesizing these derivatives is also taught. In addition, pharmaceutical compositions that include a therapeutically effective amount of at least one of these derivatives and a pharmaceutically acceptable carrier. A method for the use of these pharmaceutical compositions and compounds is taught, wherein a therapeutically effective amount is administered to an animal having solid tumor cancer. The pharmaceutical composition or compound can be re-administered to the animal until a desired treatment or result is accomplished.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.