Patent · US Expired

PROCESSING FOR PRODUCING OF DROSPIRENONE (6β, 7β, 15β, 16β-DIMETHYLENE-3-OXO-17α-PREGN-4-EN-21, 17-CARBOLACTONE, DRSP) AS WELL AS 7α-(3-HYDOXY-1-PROPLY)-6β, 7β; 15β, 16β-DIMETHYLENE-5β-ANDROSTANE-3β, 5,17β-TRIOL(ZK 92836) AND 6β, 7β; 15β, 16β-DIMETHYLENE-5β-HYDROXY

US6933395B1 · kind B1 · utility

7Cited by

6References

6Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Jörg MOHR · Berlin, DE
Klaus Nickisch · Berlin, DE

Key dates

Filing date	Aug 18, 2000
Grant date	Aug 23, 2005
Priority date	—
Expiry date	Aug 18, 2020

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J53/008
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Process for the production of drospirenone (6β,7β; 15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone, DRSP) (1) and 7α-(3-hydroxy-1-propyl)-6β,7β; 15β,16β-dimethylene-5β-androstane-3β,5,17β-triol (ZK 92836) and 6β,7β; 15β,16β-dimethylene-5β-hydroxy-3-oxo-17α-androstane-21,17-carbolactone (ZK 90965) as intermediate products of the process.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.