Methods for designing agents that interact with MMP-13
US6934639B1 · kind B1 · utility
97Cited by
3References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 25, 2000 |
| Grant date | Aug 23, 2005 |
| Priority date | — |
| Expiry date | Feb 25, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2299/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the three dimensional structure of human collagenase 3 (MMP-13), as well as to (i) methods of using the MMP-13 structure to rationally design or identify compounds or molecules that inhibit or activate MMP-13 activity, and (ii) compounds identified using said methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.