Adeno-associated viral vector-mediated delivery of DNA to cells of the liver

US6936243B2 · kind B2 · utility

Assignees

• University of Washington · US
• Cell Genesys, Inc. · US

Inventors

• Richard Snyder · Gainesville, US
• Lawrence K. Cohen · Oakland, US
• Mark A. Kay · Los Altos, US
• Olivier Danos · New York, US
• Arthur Richard Daniel Thompson · Lancaster, US

Key dates

• Filing date: May 22, 2000
• Grant date: Aug 30, 2005
• Expiry date: May 22, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2750/14143
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The instant invention provides methods of expressing polynucleotides in the cells of the liver comprising administering viral particles comprising a recombinant AAV vector into a mammal, preferably a human.