Detection of antibody mediated inflammatory auto-immune disorders
US6936426B2 · kind B2 · utility
3Cited by
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4Claims
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Key dates
| Filing date | Oct 19, 2001 |
| Grant date | Aug 30, 2005 |
| Priority date | — |
| Expiry date | Aug 21, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes a method to detect connective tissue pathologies associated with Graves' disease ophthalmopathy and other antibody mediated inflammatory autoimmune diseases. The detection method comprises obtaining a sample from a patient suffering from an antibody-mediated inflammatory autoimmune disorder and measuring Interleukin 16 (IL-16) or RANTES produced by thyroid associated ophthalmopathy fibroblasts to indicate the presence or severity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.