Synergistic effects of OP/BMP morphogens and GDNF/NGF neurotrophic factors
US6936582B1 · kind B1 · utility
7Cited by
2References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1998 |
| Grant date | Aug 30, 2005 |
| Priority date | — |
| Expiry date | Sep 9, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/1875
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
OP/BMP morphogen is combined with GDNF/NGF neurotrophic factors in promoting the survival or growth, or inhibiting the death or degeneration, of mammalian cells, particularly neural cells, which express OP/BMP-activated serine/threonine kinase receptors and GDNF/NGF-activated tyrosine kinase receptors. Also discosed are methods for the treatment of such cells, including treatments for mammals afflicted with, or at imminent risk of, damage or injury to, such cells, as well as new pharmaceutical preparations for such treatments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.