Compound containing a labile disulfide bond
US6936729B2 · kind B2 · utility
6Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 28, 2001 |
| Grant date | Aug 30, 2005 |
| Priority date | — |
| Expiry date | Feb 8, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/62
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A labile disulfide-containing compound under physiological conditions, comprising: the disulfide-containing compound having a labile disulfide bond that is either a disulfide bond that is cleaved more rapidly than oxidized glutathione or a disulfide bond constructed from thiols in which one of the constituent thiols has a lower pKa than glutathione or a disulfide bond that is activated by intramolecular attack from a free thiol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.