Expansion of hematopoietic cells using midkine or pleiotrophin
US6939669B2 · kind B2 · utility
0Cited by
9References
8Claims
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Assignee
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Key dates
| Filing date | Feb 8, 2002 |
| Grant date | Sep 6, 2005 |
| Priority date | — |
| Expiry date | Jul 9, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/23
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel use of the MK family that is used alone as an agent for proliferating hematopoietic stem cells and hematopoietic precursor cells. The invention also provides an agent for remarkably enhancing the above-described effect for promoting the proliferation of hematopoietic stem cells and hematopoietic precursor cells, comprising the MK family in combination with known hematopoietic factors such as IL-3, IL-6, G-CSF, GM-CSF, M-CSF, SCF, and EPO.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.