Non-sedating barbituric acid derivatives
US6939873B2 · kind B2 · utility
8Cited by
18References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 30, 2003 |
| Grant date | Sep 6, 2005 |
| Priority date | — |
| Expiry date | May 22, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/515
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel non-sedating barbituric acid derivatives, pharmaceutical compositions containing them and methods of neuroprotection in cases of cerebral ischemia, head trauma and other acute neurologic injuries, and prevention of resulting neuronal damage. The invention also relates to the use of non-sedating barbituric acid derivatives given in a manner and dosage effective to produce blood levels and brain levels of these drugs and/or their active metabolites sufficient to provide a therapeutic effect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.