Process for producing 4-dimethyl amino pyridine (4-DMAP)
US6939972B2 · kind B2 · utility
2Cited by
4References
9Claims
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Key dates
| Filing date | Apr 4, 2003 |
| Grant date | Sep 6, 2005 |
| Priority date | — |
| Expiry date | Apr 4, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/74
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An improved process for producing 4-dimethyl amino pyridine is provided. The process comprises quaternizing pyridine with a suitable quaternizing agent in the presence of organic solvent, isolating the resulting salt and aminating the salt, N-[4-pyridyl] pyridinium chloride hydrochloride, with N,N-dimethyl formamide. The resultant reaction mass is hydrolysed in the presence of a base, extracted with an aromatic solvent and distilled under vacuum to produce 4-dimethyl amino pyridine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.