N-terminal modifications of RANTES and methods of use
US6942852B1 · kind B1 · utility
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4References
22Claims
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Key dates
| Filing date | Oct 4, 2000 |
| Grant date | Sep 13, 2005 |
| Priority date | — |
| Expiry date | Feb 20, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
N-terminally modified RANTES derivatives are disclosed. The derivatives effectively block the inflammatory effects of RANTES, and are useful for the treatment of asthma, allergic rhinitis, atopic dermatitis, atheroma/atherosclerosis, and rheumatoid arthritis. Additionally, the compounds are useful for the treatment of HIV infection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.