Patent · US Expired

Method of producing antihypercholesterolemic agents

US6943017B2 · kind B2 · utility

4Cited by

15References

6Claims

0Family size

Assignee

Wisconsin Alumni Research Foundation · US

Inventors

Charles R. Hutchinson · Madison, US
Jonathan Kennedy · Grass Valley, US
Cheonseok Park · Seoul, KR

Key dates

Filing date	Mar 28, 2002
Grant date	Sep 13, 2005
Priority date	—
Expiry date	Oct 20, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12R2001/66
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method of increasing the production of lovastatin or monacolin J in a lovastatin-producing or non-lovastatin-producing organism is disclosed. In one embodiment, the method comprises the steps of transforming an organism with the A. terreus D4B segment, wherein the segment is translated and where an increase in lovastatin production occurs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.