Patent · US Expired

Death domain containing receptor-4 antibodies

US6943020B2 · kind B2 · utility

7Cited by
4References
52Claims
0Family size

Assignees

Inventors

Key dates

Filing dateAug 23, 2002
Grant dateSep 13, 2005
Priority date
Expiry dateFeb 7, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K14/70578
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to novel Death Domain Containing Receptor-4 (DR4) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR4 proteins. DR4 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR4 activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.