Benzimidazolone peptidomimetics as thrombin receptor antagonists
US6943149B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 17, 2003 |
| Grant date | Sep 13, 2005 |
| Priority date | — |
| Expiry date | Oct 27, 2023 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH05K3/4092
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to novel benzimidazolone peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, Angiogenesis related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted benzimidazolone peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.