Patent · US Expired

Pyrimidine and triazine kinase inhibitors

US6943161B2 · kind B2 · utility

2Cited by
8References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 28, 2002
Grant dateSep 13, 2005
Priority date
Expiry dateJun 28, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds that selectively inhibit inappropriate kinase activities and methods for their preparation are disclosed. In one embodiment, the compounds are represented by Formula I, As selective inhibitors of inappropriate kinase activities, the compounds of the present invention are useful in the treatment of conditions associated with such activity, including, but not limited to, inflammatory and autoimmune responses, diabetes, asthma, psoriasis, inflammatory bowel disease, transplantation rejection, and tumor metastasis. Also disclosed are methods of inhibiting inappropriate kinase activities and methods of treating conditions associated with such activities.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.