Biurethane derivatives

US6943179B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Werner Mederski · Zwingenberg, DE
• Bertram Cezanne · Mörfelden, DE
• Dieter Dorsch · Ober-Ramstadt, DE
• Christos Tsaklakidis · Weinheim, DE
• Johannes Gleitz · Darmstadt, DE
• Christopher Barnes · Bad Soden, DE

Key dates

• Filing date: Feb 27, 2002
• Grant date: Sep 13, 2005
• Expiry date: Apr 27, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel compounds of the formula I in which X, Y, Z, R, R1, R2 and R3 are as defined in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of tromboembolic diseases and for the treatment of tumors