Indocyanine green (ICG) compositions and related methods of use
US6944493B2 · kind B2 · utility
44Cited by
64References
97Claims
0Family size
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Key dates
| Filing date | Dec 27, 2001 |
| Grant date | Sep 13, 2005 |
| Priority date | — |
| Expiry date | Mar 5, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0084
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Aqueous indocyanine green (ICG) composition exhibiting enhanced stability, as well as enhanced ICG concentration, as compared to presently available ICG products. The composition comprises an aqueous ICG composition comprising ICG at a concentration of at least about 10 mg/ml and an aqueous diluent, wherein the composition is stable for at least 24 hours. Diagnostic and therapeutic methods for using these aqueous compositions are also contemplated, e.g., angiography, dye-enhanced photocoagulation, photodynamic therapy, for a variety of conditions, including Age-Related Macular Degeneration (ARMD), lesions and tumors.
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