Transition state analogs
US6946272B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 30, 1999 |
| Grant date | Sep 20, 2005 |
| Priority date | — |
| Expiry date | Nov 21, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/96472
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Antigens capable of eliciting antibodies which can catalyze chemical reactions, in particular, the cleavage or formation of a peptide linkage, comprising a hapten or a hapten and a suitable carrier molecule are disclosed. Haptens include, among others, silicon and boron containing compounds. Antibodies which are catalytically active for chemical reactions, in particular, the cleavage or formation of a selected peptide linkage or an ester bond, and which are elicited by such antigens are disclosed as well as methods for producing the antibodies and methods for catalyzing the cleavage or formation of a peptide linkage or in ester bond in a molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.