Interstrand crosslinking agents for DNA and compounds therefor
US6946455B2 · kind B2 · utility
16Cited by
0References
12Claims
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Key dates
| Filing date | May 1, 2001 |
| Grant date | Sep 20, 2005 |
| Priority date | — |
| Expiry date | Mar 4, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds represented by the general formula (I): which two DNA strands can be interstrand-crossliked:A-L-B-X-B-L-A (I)wherein B represents a chemical structure capable of recognizing the nucleotide sequence of DNA; A represents a chemical structure capable of binding to one of the bases of DNA; L represents a linker by which the chemical structures of A and B can be linked to each other; X represents a spacer by which the A-L-B components can be linked to each other. A method of interstrand-crosslinking DNA by using these compounds; and medicinal compositions containing interstarand-crosslinking agents of DNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.