FadD15 gene of Corynebacterium glutamicum, encoding an acyl-CoA synthase polypeptide

US6949374B2 · kind B2 · utility

Assignee

• Degussa AG · DE

Inventors

• Madhavan Nampoothiri K. · Thrissur, IN
• Bettina Mockel · Bielefeld, DE
• Walter Pfefferle · Bodenwerder, DE
• Lothar Eggeling · Jülich, DE
• Hermann Sahm · Jülich, DE

Key dates

• Filing date: May 16, 2001
• Grant date: Sep 27, 2005
• Expiry date: Sep 27, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P13/08
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a genetically modified coryneform bacterium, the fadD15 gene of which is amplified, and an isolated polynucleotide which codes for acyl-CoA synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the fadD15 gene in the bacteria and the use of the polynucleotide as a primer or hybridization probe.