Effectors of dipeptidyl peptidase IV for topical use

US6949515B2 · kind B2 · utility

Assignee

• PROBIODRUG AG · DE

Inventors

• Hans-Ulrich Demuth · Halle (Saale), DE
• Torsten Hoffmann · Weil am Rhein, DE
• Dagmar Schlenzig · Bodenwerder, DE
• Ulrich Heiser · Halle (Saale), DE

Key dates

• Filing date: Feb 22, 2002
• Grant date: Sep 27, 2005
• Expiry date: Aug 1, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to compounds for topically influencing the activity of dipeptidyl peptidase of the general formula The invention further relates to the use of said compounds for targeted intervention in local immunological processes (chemotaxis, inflammatory processes, autoimmune diseases), as well as effective and targeted treatment of pathophysiological and physiological processes related thereto (psoriasis, periodontitis, arthritis, allergies, inflammation), inter alia.