Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using aminoindane derivatives
US6949575B2 · kind B2 · utility
13Cited by
6References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 25, 2001 |
| Grant date | Sep 27, 2005 |
| Priority date | — |
| Expiry date | Aug 9, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds of Formula (I) and a method of treating Alzheimer's disease using a compound of Formula (I), wherein: R1 and R2 include alkyl and phenylalkyl; R3 is hydrogen or alkyl; and R4 and R5 include alkyl, alkoxy, carboxyl, alkoxycarbonyl, and nitro. Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of Formula (I) and a method of imaging amyloid deposits using compounds of Formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.