Imidazonaphthyridines

US6949646B2 · kind B2 · utility

Assignee

• 3M INNOVATIVE PROPERTIES COMPANY · US

Inventors

• John F. Gerster · Woodbury, US
• Kyle J. Lindstrom · Houlton, US
• Stephen L. Crooks · Mahtomedi, US
• Philip D. Heppner · Woodbury, US
• Gregory J. Marszalek · Windom, US
• Peter Maye · Windom, US
• Bryon A. Merrill · River Falls, US
• John Mickelson · Mattawan, US
• Michael J. Rice · Oakdale, US

Key dates

• Filing date: Dec 3, 2004
• Grant date: Sep 27, 2005
• Expiry date: Dec 3, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.