Carboxylic acid-type lipid
US6949663B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 9, 2001 |
| Grant date | Sep 27, 2005 |
| Priority date | — |
| Expiry date | Nov 9, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
As a negatively charged lipid that can stably add negative charges to the surface of vesicles without side effects, the carboxyl acid-type lipid of the following general formula [1]: [wherein R1, R2 and R3 represent substituents of which one is represented by the following general formula [X]: (wherein M is a hydrogen atom or monovalent cation, and m is an integer of 1 to 5 that represents the methylene chain length), and the other two are chained hydrocarbon groups; A1, A2 and A3 are the same or different substituents selected from the group consisting of C(O)O, CONH or NHCO; and n is an integer of 1 to 3 that represents the methylene chain length) is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.