Process for producing 5-(3-cyanophenyl)-3-formylbenzoic acid compound
US6949668B2 · kind B2 · utility
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Key dates
| Filing date | Nov 30, 2001 |
| Grant date | Sep 27, 2005 |
| Priority date | — |
| Expiry date | Nov 30, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/57
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 5-(3-cyanophenyl)-3-formylbenzoic acid compound of the formula (IV) is prepared by reacting a 5-bromo-3-(hydroxymethyl)benzoic acid compound of the formula (I) with manganese dioxide to provide a 5-bromo-3-formylbenzoic acid compound of the formula (II), and then reacting the resultant compound of the formula (II) with 3-cyanophenylboronic acid of the formula (III) in the presence of a palladium complex. R is a H atom or a C1-C10 alkyl group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.