Use of novel metalloporphyrins as imageable tumor-targeting agents for radiation therapy
US6951640B2 · kind B2 · utility
3Cited by
3References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 27, 2003 |
| Grant date | Oct 4, 2005 |
| Priority date | — |
| Expiry date | Dec 10, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention covers halogenated derivatives of boronated phorphyrins containing multiple carborane cages having the formula which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron-capture therapy and photodynamic therapy. The present invention also covers methods for using these halogenated derivatives of boronated porphyrins in tumor imaging and cancer treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.