Detection of antibodies to glycosphingolipids using solid-phase reactants coated with carbonyl groups
US6951763B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jun 10, 2003 |
| Grant date | Oct 4, 2005 |
| Priority date | — |
| Expiry date | Jun 10, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/811
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods of detecting antibodies to one or more glycosphingolipid(s) of interest in a sample are disclosed which comprise using a solid-phase reactant having carbonyl groups attached theron, and the glycosphingolipid(s) of interest linked to the solid-phase reactant by an amide bond between an amino group of the glycosphingolipid of interest and a carbonyl group attached to the solid-phase reactant. The methods of detecting antibodies to glycosphingolipid(s) of interest can be used in methods of diagnosing autoimmune diseases in an individual.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.