Betamimetics with a prolonged duration of activity, processes for preparing them, and their use as pharmaceutical compositions

US6951888B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Frank Buettner · Biberach an der Riß, DE
• Ingo Konetzki · Warthausen, DE
• Kurt Schromm · Ingelheim am Rhein, DE
• Hermann Schollenberger · Ingelheim am Rhein, DE
• Sabine Pestel · Biberach, DE
• Andreas Schnapp · Biberach, DE
• Thierry Bouyssou · Mietingen, DE
• Claudia Heine · Biberach, DE

Key dates

• Filing date: Sep 19, 2003
• Grant date: Oct 4, 2005
• Expiry date: Sep 19, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A compound of formula 1 wherein: R1 is C1-C4-alkyl; R2 is C1-C4-alkyl; and R3 is C1-C4-alkyl or phenyl, each optionally mono- or polysubstituted, or R2 and R3 together are —CH2—CH2— or —CH2—CH2—CH2—, or the corresponding acid addition salt with a pharmacologically acceptable acid, processes for preparing such compounds, pharmaceutical compositions containing such compounds, and their use in the treatment of inflammatory and obstructive respiratory diseases.