Patent · US Expired

Method of preventing transport of a neurotropic virus and identifying agents for achieving same

US6953661B1 · kind B1 · utility

4Cited by

4References

6Claims

0Family size

Assignees

Westmead Hospital · AU
The University of Sydney · AU

Inventors

Russell John Diefenbach · Parramatta, AU
Monica Miranda-Saksena · Parramatta, AU
Eve Margaret Diefenbach · Parramatta, AU
David James Holland · Auckland, NZ
Anthony Lawrence Cunningham · Melbourne, AU
Mark Penfold · Mountain View, US
Patricia Joan Armati · Sydney, AU

Key dates

Filing date	Jul 20, 2000
Grant date	Oct 11, 2005
Priority date	—
Expiry date	Jul 20, 2020

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2710/16643
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method of preventing transport of a Herpes simplex virus within a neuron, comprising preventing interaction between a structural tegument protein US11 of the virus and a motor protein, Kinesin in the neuron such that virus transport in the neuron is prevented. An antiviral composition is also provided, comprising a compound capable of preventing interaction between a structural tegument protein of a neurotropic virus and a neuron or cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.