Method for the recombinant production of 1,3-propanediol
US6953684B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1997 |
| Grant date | Oct 11, 2005 |
| Priority date | — |
| Expiry date | Jun 21, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/824
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a microorganism for the production of 1,3-propanediol from a variety of carbon sources in an organism capable of 1,3-propanediol production and comprising a) at least one gene encoding a dehydratase activity; b) at least one gene encoding a glycerol-3-phosphatase; and c) at least one gene encoding protein X. The protein X may be derived from a Klebsiella or Citrobacter gene cluster. The recombinant microorganism may further comprise d) at least one gene encoding a protein having at least 50% similarity to a protein selected from the group consisting of protein 1 (SEQ ID NO:60 or SEQ ID NO:61), of protein 2 (SEQ ID NO:62 or SEQ ID NO:63) and of protein 3 (SEQ ID NO:64 or SEQ ID NO:65) from Klebsiella or Citrobacter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.