Cross-linked polysaccharide drug carrier
US6953784B2 · kind B2 · utility
15Cited by
9References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 3, 2003 |
| Grant date | Oct 11, 2005 |
| Priority date | — |
| Expiry date | Oct 3, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0063
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A carrier and a method for preparing it are provided for use in the delivery of therapeutic agents. A polysaccharide is reacted with an oxidizing agent to open sugar rings on the polysaccharide to form aldehyde groups. The aldehyde groups are reacted to form covalent oxime linkages with a second polysaccharide and each of the first and second polysaccharide is selected from the group consisting of hyaluronic acid, dextran, dextran sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparan, heparan sulfate and alginate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.