Linkage of agents to body tissue using microparticles and transglutaminase
US6958148B1 · kind B1 · utility
47Cited by
282References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 21, 2000 |
| Grant date | Oct 25, 2005 |
| Priority date | — |
| Expiry date | Jul 21, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/812
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods, products and kits are provided for attaching agents to a body tissue surface via microparticles using endogenous or exogenous transglutaminase. The microparticles have surface available transglutaminase substrate reactive groups. In an embodiment, the groups are part of a polymer containing at least two contiguous linked lysines or at least three contiguous linked glutamines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.