Miniprotein ligands and other polypeptides and methods for making and using same
US6958151B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 17, 2003 |
| Grant date | Oct 25, 2005 |
| Priority date | — |
| Expiry date | Mar 17, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are polypeptides which include an amino acid sequence corresponding to CCXXXCKEGXXC (SEQ ID NO:1). Also disclosed are methods for inhibiting the activity of a flavivirus or other virus by contacting the virus with a miniprotein ligand under conditions effective for the miniprotein ligand to bind to the virus. Methods for detecting a flavivirus or other virus in a sample by contacting the sample with a miniprotein ligand and determining whether the miniprotein ligand is bound to a flavivirus or other virus as also disclosed, as are methods of assessing a compound's usefulness in inhibiting the activity of a flavivirus or other virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.