Process for preparing vanillylamine hydrochloride

US6958418B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Oliver Meyer · Ingelheim am Rhein, DE
• Ingo Heddesheimer · Monzingen, DE

Key dates

• Filing date: Jun 9, 2005
• Grant date: Oct 25, 2005
• Expiry date: Jun 9, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C217/58
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Process for preparing vanillylamine or one of the salts thereof by reacting vanillin with hydroxylamine or the salts thereof in the presence of an organic salt, which may optionally be produced in situ, wherein the reaction is carried out in an inorganic or organic acid as diluent, and subsequently hydrogenating the resulting vanillyloxime with hydrogen in the presence of a suitable catalyst and an organic and/or inorganic acid.