Preparation and use of imidazole derivatives for treatment of obesity

US6960601B2 · kind B2 · utility

Assignee

• Bayer Pharmaceuticals Corporation · US

Inventors

• Roger Smith · Madison, US
• Stephen O'Connor · Wilmette, US
• Stephan-Nicholas Wirtz · Wuppertal, DE
• Wai C. Wong · Newark, US
• Soongyu Choi · Skillman, US
• Harold Kluender · Hartland, US
• Ning Su · Hamden, US
• Gan Wang · Wallingford, US
• Furahi Achebe · West Haven, US
• Shihong Ying · Orange, US

Key dates

• Filing date: Sep 24, 2002
• Grant date: Nov 1, 2005
• Expiry date: Jan 9, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to substituted imidazole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.