1-diphenylmethyl-pyrazole derivatives as opioid receptor ligands
US6960609B2 · kind B2 · utility
1Cited by
1References
6Claims
0Family size
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Key dates
| Filing date | Jul 23, 2002 |
| Grant date | Nov 1, 2005 |
| Priority date | — |
| Expiry date | Jul 23, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to 1-diphenylmethyl-pyrazole derivatives of formula (I): and pharmaceutically acceptable salts thereof; wherein R1, R2, R3, R4 and R5 are defined herein, as ligands for opioid receptors, particularly the delta opioid receptor. The compounds of the invention have a broad range of therapeutic uses in the area of addictions, analgesia, immunotherapy, shock and brain injuries, neurological dysfunction, gastrointestinal dysfunction, among others.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.