Chimeric flavivirus vaccines
US6962708B1 · kind B1 · utility
18Cited by
3References
14Claims
0Family size
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Inventors
Key dates
| Filing date | Jul 23, 1998 |
| Grant date | Nov 8, 2005 |
| Priority date | — |
| Expiry date | Jul 23, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A chimeric live, infectious, attenuated virus containing a yellow fever virus, in which the nucleotide sequence for a prM-E protein is either deleted, truncated, or mutated, so that functional prM-E protein is not expressed, and integrated into the genome of the yellow fever virus, a nucleotide sequence encoding a prM-E protein of a second, different flavivirus, so that the prM-E protein of the second flavivirus is expressed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.